产品货号：
GS4423
中文名称：
重组人IP-10/CXCL10
英文名称：
Recombinant Human gamma-Interferon Inducible Protein 10/CXCL10
产品规格：
5μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 8.6kDa,a single non-glycosylated polypeptide chain containing 77 amino acids.
储存条件：冷冻（-20℃）
概述
CXCL10 also known as IP-10 is belonging to the CXC chemokine family.It is encoded by the CXCL10 gene.CXCL10 was originally identified in monocytes,endothelial cells and fibroblasts as a responsor to IFN-γ.This chemokine elicits its effects by binding to the cell surface chemokine receptor CXCR3.CXCL10 has been shown to be a chemoattractant for activated T-lymphocytes and monocytes/macrophages.It also has other roles,such as promotion of T cell adhesion to endothelial cells,and inhibition of bone marrow colony formation and angiogenesis.The mouse homologue of human IP-10,Crg-2,has been cloned and shown to share approximately 67%amino acid sequence identity with human IP-10.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组人IP-10/CXCL10，IP-10/CXCL10, Human
储存条件：冷冻（-20℃）
概述
CXCL10 also known as IP-10 is belonging to the CXC chemokine family.It is encoded by the CXCL10 gene.CXCL10 was originally identified in monocytes,endothelial cells and fibroblasts as a responsor to IFN-γ.This chemokine elicits its effects by binding to the cell surface chemokine receptor CXCR3.CXCL10 has been shown to be a chemoattractant for activated T-lymphocytes and monocytes/macrophages.It also has other roles,such as promotion of T cell adhesion to endothelial cells,and inhibition of bone marrow colony formation and angiogenesis.The mouse homologue of human IP-10,Crg-2,has been cloned and shown to share approximately 67%amino acid sequence identity with human IP-10.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞97%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human peripheral blood T-lymphocytes is in a concentration range of 10-50ng/ml. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in 20mMPB,pH 7.4,50 mM NaCl. |
| 内毒素 | Less than 1 EU/μg of rHuIP-10/CXCL10 as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | VPLSRTVRCT CISISNQPVN PRSLEKLEII PASQFCPRVE IIATMKKKGE KRCLNPESKA IKNLLKAVSK EMSKRSP |
相关搜索：重组人IP-10/CXCL10，IP-10/CXCL10, Human